Breast cancer prognostication and prediction in the postgenomic era

Breast Cancer Prognostication and Risk Prediction in the Post-Genomic Era

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

Breast cancer prognostication and prediction: are we making progress?

Currently, much effort is being invested in the identification of new, accurate prognostic and predictive factors in breast cancer. Prognostic factors assess the patient's risk of relapse based on indicators such as intrinsic tumor biology and disease stage at diagnosis, and are traditionally used to identify patients who can be spared unnecessary adjuvant therapy based only on the risk of rela...

Diet, nutrition, and cancer prevention: the postgenomic era.

The genomic era of human nutrition is upon us: the human genome and several plant genomes have been characterized, and genetically modified foods are now abundantly available in the marketplace. The link between diet and cancer is well established, and new genomic technologies have made possible the investigation of nutritional modulation of the carcinogenesis pathway with nutrients, micronutri...

Prognosticating Retinal Dystrophies in the Postgenomic Era

I nherited retinal dystrophies are a genetically heterogeneous group of disorders. They can be classified in various ways including by clinical findings, electrophysiologic findings, or by inheritance patterns. One of the most important early steps in the clinical evaluation of retinal dystrophy patients is to obtain a family history. If possible, family members can be examined as well to form ...